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BMCBI
2008
78views more  BMCBI 2008»
15 years 2 months ago
A new protein linear motif benchmark for multiple sequence alignment software
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
Emmanuel Perrodou, Claudia Chica, Olivier Poch, To...
127
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BMCBI
2007
110views more  BMCBI 2007»
15 years 2 months ago
Analysis of feedback loops and robustness in network evolution based on Boolean models
Background: Many biological networks such as protein-protein interaction networks, signaling networks, and metabolic networks have topological characteristics of a scale-free degr...
Yung-Keun Kwon, Kwang-Hyun Cho
BMCBI
2007
123views more  BMCBI 2007»
15 years 2 months ago
PedGenie: meta genetic association testing in mixed family and case-control designs
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...
BMCBI
2008
132views more  BMCBI 2008»
15 years 2 months ago
Computational cluster validation for microarray data analysis: experimental assessment of Clest, Consensus Clustering, Figure of
Background: Inferring cluster structure in microarray datasets is a fundamental task for the so-called -omic sciences. It is also a fundamental question in Statistics, Data Analys...
Raffaele Giancarlo, Davide Scaturro, Filippo Utro
131
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BMCBI
2007
117views more  BMCBI 2007»
15 years 2 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins