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BMCBI
2008
78views more  BMCBI 2008»
15 years 4 months ago
Deducing topology of protein-protein interaction networks from experimentally measured sub-networks
Background: Protein-protein interaction networks are commonly sampled using yeast two hybrid approaches. However, whether topological information reaped from these experimentallym...
Ling Yang, Thomas M. Vondriska, Zhangang Han, W. R...
BMCBI
2008
158views more  BMCBI 2008»
15 years 4 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
ECCC
2010
80views more  ECCC 2010»
15 years 4 months ago
Regret Minimization for Online Buffering Problems Using the Weighted Majority Algorithm
Suppose a decision maker has to purchase a commodity over time with varying prices and demands. In particular, the price per unit might depend on the amount purchased and this pri...
Melanie Winkler, Berthold Vöcking, Sascha Geu...
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BMCBI
2007
94views more  BMCBI 2007»
15 years 4 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
JCB
2007
130views more  JCB 2007»
15 years 3 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey