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» Identifying Structural Motifs in Proteins
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BMCBI
2002
101views more  BMCBI 2002»
13 years 9 months ago
Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
Background: Total sequence decomposition, using the web-based MASIA tool, identifies areas of conservation in aligned protein sequences. By structurally annotating these motifs, t...
Catherine H. Schein, Numan Özgün, Tadahi...
ALMOB
2007
74views more  ALMOB 2007»
13 years 10 months ago
Evaluating deterministic motif significance measures in protein databases
Background: Assessing the outcome of motif mining algorithms is an essential task, as the number of reported motifs can be very large. Significance measures play a central role in...
Pedro Gabriel Ferreira, Paulo J. Azevedo
BMCBI
2007
96views more  BMCBI 2007»
13 years 9 months ago
Structure and function predictions of the Msa protein in Staphylococcus aureus
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
Vijayaraj Nagarajan, Mohamed O. Elasri
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
13 years 10 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2007
134views more  BMCBI 2007»
13 years 10 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...