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» Identifying Structural Motifs in Proteins
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BMCBI
2007
107views more  BMCBI 2007»
13 years 10 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
CSB
2003
IEEE
14 years 3 months ago
Initial Large-scale Exploration of Protein-protein Interactions in Human Brain
Study of protein interaction networks is crucial to post-genomic systems biology. Aided by highthroughput screening technologies, biologists are rapidly accumulating protein-prote...
Jake Yue Chen, Andrey Y. Sivachenko, Russell Bell,...
BIBE
2006
IEEE
184views Bioinformatics» more  BIBE 2006»
14 years 4 months ago
A Language Modeling Text Mining Approach to the Annotation of Protein Community
This paper discusses an ontology based language modeling text mining approach to the annotation of protein community. Communities appear to play an important role in the functional...
Xiaodan Zhang, Daniel Duanqing Wu, Xiaohua Zhou, X...
NAR
2011
257views Computer Vision» more  NAR 2011»
13 years 24 days ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...
BIOINFORMATICS
2006
134views more  BIOINFORMATICS 2006»
13 years 10 months ago
HaptenDB: a comprehensive database of haptens, carrier proteins and anti-hapten antibodies
The key requirement for successful immunochemical assay is the availability of antibodies with high specificity and desired affinity. Small molecules, when used as haptens, are no...
Mahender Kumar Singh, Shilpy Srivastava, G. P. S. ...