Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characte...
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
— Heterogeneous genome-wide data sources capture information on various aspects of complex biological systems. For instance, transcriptome, interactome and phenome-level informat...
Background: Structure identification of dynamic models for complex biological systems is the cornerstone of their reverse engineering. Biochemical Systems Theory (BST) offers a pa...
Marco Vilela, Carlos Cristiano H. Borges, Susana V...
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...