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» Indexing and Searching a Mass Spectrometry Database
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BMCBI
2010
140views more  BMCBI 2010»
13 years 5 months ago
An improved machine learning protocol for the identification of correct Sequest search results
Background: Mass spectrometry has become a standard method by which the proteomic profile of cell or tissue samples is characterized. To fully take advantage of tandem mass spectr...
Morten Kallberg, Hui Lu
SISAP
2010
IEEE
135views Data Mining» more  SISAP 2010»
13 years 5 months ago
Improving the similarity search of tandem mass spectra using metric access methods
In biological applications, the tandem mass spectrometry is a widely used method for determining protein and peptide sequences from an ”in vitro” sample. The sequences are not...
Jiri Novák, Tomás Skopal, David Hoks...
BMCBI
2007
166views more  BMCBI 2007»
13 years 7 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2007
155views more  BMCBI 2007»
13 years 7 months ago
ProMEX: a mass spectral reference database for proteins and protein phosphorylation sites
Background: In the last decade, techniques were established for the large scale genome-wide analysis of proteins, RNA, and metabolites, and database solutions have been developed ...
Jan Hummel, Michaela Niemann, Stefanie Wienkoop, W...
BMCBI
2011
12 years 11 months ago
PI: An open-source software package for validation of the SEQUEST result and visualization of mass spectrum
Background: Tandem mass spectrometry (MS/MS) has emerged as the leading method for high- throughput protein identification in proteomics. Recent technological breakthroughs have d...
Yantao Qiao, Hong Zhang, Dongbo Bu, Shiwei Sun