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BMCBI
2005
114views more  BMCBI 2005»
13 years 7 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
GLVLSI
2003
IEEE
175views VLSI» more  GLVLSI 2003»
14 years 1 months ago
A custom FPGA for the simulation of gene regulatory networks
We present a unique FPGA that uses a mix of digital and large-signal analog computation for the simulation of gene regulatory networks. The prototype IC consists of a 4x5 array of...
Ilias Tagkopoulos, Charles A. Zukowski, German Cav...
CMSB
2006
Springer
13 years 11 months ago
Regulatory Network Reconstruction Using Stochastic Logical Networks
Abstract. This paper presents a method for regulatory network reconstruction from experimental data. We propose a mathematical model for regulatory interactions, based on the work ...
Bartek Wilczynski, Jerzy Tiuryn
RECOMB
2004
Springer
14 years 8 months ago
Probabilistic discovery of overlapping cellular processes and their regulation
In this paper, we explore modeling overlapping biological processes. We discuss a probabilistic model of overlapping biological processes, gene membership in those processes, and ...
Alexis Battle, Eran Segal, Daphne Koller
BMCBI
2010
240views more  BMCBI 2010»
13 years 7 months ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...