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BMCBI
2007
166views more  BMCBI 2007»
13 years 7 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2010
240views more  BMCBI 2010»
13 years 7 months ago
TAM: A method for enrichment and depletion analysis of a microRNA category in a list of microRNAs
Background: MicroRNAs (miRNAs) are a class of important gene regulators. The number of identified miRNAs has been increasing dramatically in recent years. An emerging major challe...
Ming Lu, Bing Shi, Juan Wang, Qun Cao, Qinghua Cui
BMCBI
2004
135views more  BMCBI 2004»
13 years 7 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
BMCBI
2010
127views more  BMCBI 2010»
13 years 7 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
14 years 25 days ago
Statistical Inference for Well-ordered Structures in Nucleotide Sequences
Distinct, local structures are frequently correlated with functional RNA elements involved in posttranscriptional regulation of gene expression. Discovery of microRNAs (miRNAs) su...
Shu-Yun Le, Jih-H. Chen, Jacob V. Maizel