Motivation: Enormous, and constantly increasing quantity of biological information is represented in protein interaction network databases. Most of these data are freely accessibl...
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
Markus Fischer, Quan K. Thai, Melanie Grieb, J&uum...