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BIOINFORMATICS
2011
12 years 11 months ago
When the Web meets the cell: using personalized PageRank for analyzing protein interaction networks
Motivation: Enormous, and constantly increasing quantity of biological information is represented in protein interaction network databases. Most of these data are freely accessibl...
Gábor Iván, Vince Grolmusz
BMCBI
2005
95views more  BMCBI 2005»
13 years 7 months ago
Oligomeric protein structure networks: insights into protein-protein interactions
Background: Protein-protein association is essential for a variety of cellular processes and hence a large number of investigations are being carried out to understand the princip...
K. V. Brinda, Saraswathi Vishveshwara
BMCBI
2010
146views more  BMCBI 2010»
13 years 7 months ago
Revealing and avoiding bias in semantic similarity scores for protein pairs
Background: Semantic similarity scores for protein pairs are widely applied in functional genomic researches for finding functional clusters of proteins, predicting protein functi...
Jing Wang 0004, Xianxiao Zhou, Jing Zhu, Chenggui ...
BMCBI
2007
126views more  BMCBI 2007»
13 years 7 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BMCBI
2010
178views more  BMCBI 2010»
13 years 7 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader