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BMCBI
2006
130views more  BMCBI 2006»
13 years 10 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
BMCBI
2007
114views more  BMCBI 2007»
13 years 10 months ago
Combination of scoring schemes for protein docking
Background: Docking algorithms are developed to predict in which orientation two proteins are likely to bind under natural conditions. The currently used methods usually consist o...
Philipp Heuser, Dietmar Schomburg
BMCBI
2005
97views more  BMCBI 2005»
13 years 10 months ago
The yeast kinome displays scale free topology with functional hub clusters
Background: The availability of interaction databases provides an opportunity for researchers to utilize immense amounts of data exclusively in silico. Recently there has been an ...
Robin E. C. Lee, Lynn A. Megeney
BMCBI
2005
124views more  BMCBI 2005»
13 years 10 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2004
111views more  BMCBI 2004»
13 years 10 months ago
Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network
Background: Transcriptional regulation of cellular functions is carried out through a complex network of interactions among transcription factors and the promoter regions of genes...
Radu Dobrin, Qasim K. Beg, Albert-Lászl&oac...