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BMCBI
2010
119views more  BMCBI 2010»
13 years 10 months ago
Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
Qi Liu, Qian Xu, Vincent Wenchen Zheng, Hong Xue, ...
BMCBI
2010
113views more  BMCBI 2010»
13 years 10 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...
BMCBI
2007
127views more  BMCBI 2007»
13 years 10 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...
NAR
2000
182views more  NAR 2000»
13 years 9 months ago
tmRDB (tmRNA database)
Maintained at the University of Texas Health Science Center at Tyler, Texas, the tmRNA database (tmRDB) is accessible at the URL http://psyche.uthct.edu/dbs/ tmRDB/tmRDB.html with...
Christian Zwieb, Jacek Wower
SIAMCOMP
2002
138views more  SIAMCOMP 2002»
13 years 9 months ago
Phase Change of Limit Laws in the Quicksort Recurrence under Varying Toll Functions
We characterize all limit laws of the quicksort type random variables defined recursively by Xn d = XIn + X n-1-In + Tn when the "toll function" Tn varies and satisfies ...
Hsien-Kuei Hwang, Ralph Neininger
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