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» Learning Methods for DNA Binding in Computational Biology
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ISMB
1994
15 years 6 months ago
Stochastic Motif Extraction Using Hidden Markov Model
In this paper, westudy the application of an ttMM(hidden Markov model) to the problem of representing protein sequencesby a stochastic motif. Astochastic protein motif represents ...
Yukiko Fujiwara, Minoru Asogawa, Akihiko Konagaya
RECOMB
2011
Springer
14 years 8 months ago
Rich Parameterization Improves RNA Structure Prediction
Motivation. Current approaches to RNA structure prediction range from physics-based methods, which rely on thousands of experimentally-measured thermodynamic parameters, to machin...
Shay Zakov, Yoav Goldberg, Michael Elhadad, Michal...
192
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CONSTRAINTS
2008
182views more  CONSTRAINTS 2008»
15 years 5 months ago
Constraint Programming in Structural Bioinformatics
Bioinformatics aims at applying computer science methods to the wealth of data collected in a variety of experiments in life sciences (e.g. cell and molecular biology, biochemistry...
Pedro Barahona, Ludwig Krippahl
BMCBI
2008
138views more  BMCBI 2008»
15 years 5 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
RECOMB
2009
Springer
16 years 6 months ago
Spatial Clustering of Multivariate Genomic and Epigenomic Information
The combination of fully sequence genomes and new technologies for high density arrays and ultra-rapid sequencing enables the mapping of generegulatory and epigenetics marks on a g...
Rami Jaschek, Amos Tanay