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BIOINFORMATICS
2011
13 years 3 months ago
Inverse perturbation for optimal intervention in gene regulatory networks
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
Nidhal Bouaynaya, Roman Shterenberg, Dan Schonfeld
BMCBI
2010
172views more  BMCBI 2010»
13 years 8 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
CCS
2003
ACM
14 years 1 months ago
Enhancing byte-level network intrusion detection signatures with context
Many network intrusion detection systems (NIDS) use byte sequences as signatures to detect malicious activity. While being highly efficient, they tend to suffer from a high false...
Robin Sommer, Vern Paxson
BMCBI
2008
95views more  BMCBI 2008»
13 years 8 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2007
181views more  BMCBI 2007»
13 years 8 months ago
Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases
Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
Seth I. Berger, Jeremy M. Posner, Avi Ma'ayan