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» NEC for Gene Expression Analysis
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BMCBI
2008
138views more  BMCBI 2008»
13 years 10 months ago
Combining transcriptional datasets using the generalized singular value decomposition
Background: Both microarrays and quantitative real-time PCR are convenient tools for studying the transcriptional levels of genes. The former is preferable for large scale studies...
Andreas W. Schreiber, Neil J. Shirley, Rachel A. B...
BMCBI
2008
120views more  BMCBI 2008»
13 years 10 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2007
148views more  BMCBI 2007»
13 years 10 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BMCBI
2007
129views more  BMCBI 2007»
13 years 10 months ago
A novel approach to sequence validating protein expression clones with automated decision making
Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones i...
Elena Taycher, Andreas Rolfs, Yanhui Hu, Dongmei Z...
BMCBI
2007
139views more  BMCBI 2007»
13 years 10 months ago
Bioinformatics analysis of the early inflammatory response in a rat thermal injury model
Background: Thermal injury is among the most severe forms of trauma and its effects are both local and systemic. Response to thermal injury includes cellular protection mechanisms...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Fra...