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BIOINFORMATICS
2011
13 years 2 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
SIGMOD
2012
ACM
212views Database» more  SIGMOD 2012»
12 years 1 months ago
Local structure and determinism in probabilistic databases
While extensive work has been done on evaluating queries over tuple-independent probabilistic databases, query evaluation over correlated data has received much less attention eve...
Theodoros Rekatsinas, Amol Deshpande, Lise Getoor
KDD
2007
ACM
209views Data Mining» more  KDD 2007»
14 years 11 months ago
Temporal causal modeling with graphical granger methods
The need for mining causality, beyond mere statistical correlations, for real world problems has been recognized widely. Many of these applications naturally involve temporal data...
Andrew Arnold, Yan Liu, Naoki Abe
BMCBI
2010
97views more  BMCBI 2010»
13 years 11 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
JCP
2006
157views more  JCP 2006»
13 years 10 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...