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» On the Associative Nijenhuis Relation
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BMCBI
2010
109views more  BMCBI 2010»
13 years 8 months ago
Functional characterization and topological modularity of molecular interaction networks
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
Jayesh Pandey, Mehmet Koyutürk, Ananth Grama
BMCBI
2010
202views more  BMCBI 2010»
13 years 8 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
BMCBI
2007
194views more  BMCBI 2007»
13 years 8 months ago
Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
Xin Zhao, Leo Wang-Kit Cheung
BMCBI
2010
141views more  BMCBI 2010»
13 years 8 months ago
CIG-DB: the database for human or mouse immunoglobulin and T cell receptor genes available for cancer studies
Background: Immunoglobulin (IG or antibody) and the T-cell receptor (TR) are pivotal proteins in the immune system of higher organisms. In cancer immunotherapy, the immune respons...
Yoji Nakamura, Tomoyoshi Komiyama, Motoki Furue, T...
BMCBI
2008
127views more  BMCBI 2008»
13 years 8 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...