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BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
14 years 1 months ago
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...
BMCBI
2007
114views more  BMCBI 2007»
13 years 7 months ago
Gene models from ESTs (GeneModelEST): an application on the Solanum lycopersicum genome
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
Nunzio D'Agostino, Alessandra Traini, Luigi Frusci...
RECOMB
2005
Springer
14 years 7 months ago
Learning Interpretable SVMs for Biological Sequence Classification
Background: Support Vector Machines (SVMs) ? using a variety of string kernels ? have been successfully applied to biological sequence classification problems. While SVMs achieve ...
Christin Schäfer, Gunnar Rätsch, Sö...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
NAR
2011
159views Computer Vision» more  NAR 2011»
12 years 10 months ago
SuperSweet - a resource on natural and artificial sweetening agents
A vast number of sweet tasting molecules are known, encompassing small compounds, carbohydrates, D-amino acids and large proteins. Carbohydrates play a particularly big role in hu...
Jessica Ahmed, Saskia Preissner, Mathias Dunkel, C...