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BMCBI
2010
125views more  BMCBI 2010»
13 years 2 months ago
ProbFAST: Probabilistic Functional Analysis System Tool
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
Israel T. da Silva, Ricardo Z. N. Vêncio, Th...
BMCBI
2007
132views more  BMCBI 2007»
13 years 7 months ago
Dependence of paracentric inversion rate on tract length
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...
Thomas L. York, Richard Durrett, Rasmus Nielsen
BIOINFORMATICS
2007
117views more  BIOINFORMATICS 2007»
13 years 7 months ago
Mining biological networks for unknown pathways
Biological pathways provide significant insights on the interaction mechanisms of molecules. Presently, many essential pathways still remain unknown or incomplete for newly sequen...
Ali Cakmak, Gultekin Özsoyoglu
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
NAR
2008
74views more  NAR 2008»
13 years 7 months ago
Gene Ontology annotations at SGD: new data sources and annotation methods
The Saccharomyces Genome Database (SGD; http:// www.yeastgenome.org/) collects and organizes biological information about the chromosomal features and gene products of the budding...
Eurie L. Hong, Rama Balakrishnan, Qing Dong, Karen...