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» PIR-ALN: a database of protein sequence alignments
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NAR
2008
103views more  NAR 2008»
13 years 7 months ago
The Generation Challenge Programme comparative plant stress-responsive gene catalogue
The Generation Challenge Programme (GCP; www.generationcp.org) has developed an online resource documenting stress-responsive genes comparatively across plant species. This public...
Samart Wanchana, Supat Thongjuea, Victor Jun M. Ul...
BMCBI
2006
161views more  BMCBI 2006»
13 years 7 months ago
Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome
Background: Automatic annotation of sequenced eukaryotic genomes integrates a combination of methodologies such as ab-initio methods and alignment of homologous genes and/or prote...
Alan Christoffels, Richard Bartfai, Hamsa Srinivas...
BMCBI
2004
123views more  BMCBI 2004»
13 years 7 months ago
galaxieEST: addressing EST identity through automated phylogenetic analysis
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
R. Henrik Nilsson, Balaji Rajashekar, Karl-Henrik ...
BMCBI
2002
95views more  BMCBI 2002»
13 years 7 months ago
The functional importance of disease-associated mutation
Background: For many years, scientists believed that point mutations in genes are the genetic switches for somatic and inherited diseases such as cystic fibrosis, phenylketonuria ...
Sean D. Mooney, Teri E. Klein
BMCBI
2005
100views more  BMCBI 2005»
13 years 7 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...