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BMCBI
2006
126views more  BMCBI 2006»
13 years 9 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron
BMCBI
2007
109views more  BMCBI 2007»
13 years 9 months ago
A cis-regulatory logic simulator
Background: A major goal of computational studies of gene regulation is to accurately predict the expression of genes based on the cis-regulatory content of their promoters. The d...
Robert D. Zeigler, Jason Gertz, Barak A. Cohen
BMCBI
2007
86views more  BMCBI 2007»
13 years 9 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
APBC
2004
132views Bioinformatics» more  APBC 2004»
13 years 10 months ago
A Novel Feature Selection Method to Improve Classification of Gene Expression Data
This paper introduces a novel method for minimum number of gene (feature) selection for a classification problem based on gene expression data with an objective function to maximi...
Liang Goh, Qun Song, Nikola K. Kasabov
AIME
2009
Springer
14 years 22 days ago
Effect of Background Correction on Cancer Classification with Gene Expression Data
This paper empirically compares six background correction methods aimed at removing unspecific background noise of the overall signal level measured by a scanner across microarrays...
Adelaide Freitas, Gladys Castillo, Ana São ...