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» Predicting Peroxisomal Proteins
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ALMOB
2008
127views more  ALMOB 2008»
13 years 8 months ago
HuMiTar: A sequence-based method for prediction of human microRNA targets
Background: MicroRNAs (miRs) are small noncoding RNAs that bind to complementary/partially complementary sites in the 3' untranslated regions of target genes to regulate prot...
Jishou Ruan, Hanzhe Chen, Lukasz A. Kurgan, Ke Che...
BMCBI
2010
119views more  BMCBI 2010»
13 years 8 months ago
Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
Qi Liu, Qian Xu, Vincent Wenchen Zheng, Hong Xue, ...
GECCO
2009
Springer
173views Optimization» more  GECCO 2009»
14 years 2 months ago
Creating regular expressions as mRNA motifs with GP to predict human exon splitting
Low correlation between mRNA concentrations measured at different locations for the same exon show many current Ensembl exon definitions are incomplete. Automatically created pa...
William B. Langdon, Joanna Rowsell, Andrew P. Harr...
BMCBI
2007
148views more  BMCBI 2007»
13 years 8 months ago
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
Elisabetta Sbisà, Domenico Catalano, Giorgi...
ICPR
2008
IEEE
14 years 2 months ago
Embedding HMM's-based models in a Euclidean space: The topological hidden Markov models
One of the major limitations of HMM-based models is the inability to cope with topology: When applied to a visible observation (VO) sequence, HMM-based techniques have difficulty ...
Djamel Bouchaffra