Motivation: Extracting functional information from protein–protein interactions (PPI) poses significant challenges arising from the noisy, incomplete, generic and static nature...
Abstract. Recent advances in high-throughput experimental techniques have enabled the production of a wealth of protein interaction data, rich in both quantity and variety. While t...
Allister Bernard, David S. Vaughn, Alexander J. Ha...
We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
Background: Predicting the three-dimensional structure of a protein from its amino acid sequence is a long-standing goal in computational/molecular biology. The discrimination of ...
Abstract. Side-chain prediction is an important subproblem of the general protein folding problem. Despite much progress in side-chain prediction, performance is far from satisfact...