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» Prediction of indirect interactions in proteins
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RECOMB
2007
Springer
14 years 11 months ago
Pairwise Global Alignment of Protein Interaction Networks by Matching Neighborhood Topology
We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
Rohit Singh, Jinbo Xu, Bonnie Berger
BMCBI
2010
174views more  BMCBI 2010»
13 years 11 months ago
The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
Junbai Wang
BMCBI
2010
179views more  BMCBI 2010»
13 years 11 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
RECOMB
2006
Springer
14 years 11 months ago
Integrated Protein Interaction Networks for 11 Microbes
We have combined four different types of functional genomic data to create high coverage protein interaction networks for 11 microbes. Our integration algorithm naturally handles s...
Balaji S. Srinivasan, Antal F. Novak, Jason Flanni...
NAR
2011
211views Computer Vision» more  NAR 2011»
13 years 1 months ago
DIMA 3.0: Domain Interaction Map
Domain Interaction MAp (DIMA, available at http:// webclu.bio.wzw.tum.de/dima) is a database of predicted and known interactions between protein domains. It integrates 5807 struct...
Qibin Luo, Philipp Pagel, Baiba Vilne, Dmitrij Fri...