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» Prediction of protein structural class with Rough Sets
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BMCBI
2007
105views more  BMCBI 2007»
13 years 8 months ago
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
Background: Vaccine development in the post-genomic era often begins with the in silico screening of genome information, with the most probable protective antigens being predicted...
Irini A. Doytchinova, Darren R. Flower
BMCBI
2006
143views more  BMCBI 2006»
13 years 8 months ago
Application of protein structure alignments to iterated hidden Markov model protocols for structure prediction
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
Eric D. Scheeff, Philip E. Bourne
BMCBI
2007
119views more  BMCBI 2007»
13 years 8 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
RECOMB
2009
Springer
14 years 9 months ago
Simultaneous Alignment and Folding of Protein Sequences
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Bonnie Berger, Charles W. O'Donnell, Jér&oc...
BIOCOMP
2006
13 years 10 months ago
Statistical Analysis of Long-Range Interactions in Proteins
We carry out a comprehensive study of long-range interactions on a large data set of non-homologous proteins. Our study reveals that the long-range interactions between amino acid...
Jinmiao Chen, Narendra S. Chaudhari