Complex systems exhibit emergent patterns of behavior at different levels of organization. Powerful network analysis methods, developed in physics and social sciences, have been s...
Andre Nash, Christian Bird, Earl T. Barr, Premkuma...
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
Nunzio D'Agostino, Mario Aversano, Maria Luisa Chi...
An input to the betweenness problem contains m constraints over n real variables (points). Each constraint consists of three points, where one of the points is specified to lie in...
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...