451 search results - page 17 / 91 » SAT-based protein design |
BIOCOMP
2009
13 years 8 months ago
2009
Abstract-- Stating protein design as an energy minimization in the space of amino acid sequences and rotamer combinations is usual. In the current paper an evolutionary algorithm b...
RECOMB
2007
Springer
14 years 8 months ago
2007
Springer
Our group has recently developed a compact, universal protein binding microarray (PBM) that can be used to determine the binding preferences of transcription factors (TFs) [1]. Thi...
BMCBI
2006
13 years 7 months ago
2006
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
ICCAD
2009
IEEE
13 years 5 months ago
2009
IEEE
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
JCC
2008
13 years 7 months ago
2008
: We adapt a combinatorial optimization algorithm, extremal optimization (EO), for the search problem in computational protein design. This algorithm takes advantage of the knowled...