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BIOINFORMATICS
2011
13 years 2 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
NAR
2011
340views Computer Vision» more  NAR 2011»
13 years 1 months ago
CCDB: a curated database of genes involved in cervix cancer
The Cervical Cancer gene DataBase (CCDB, http:// crdd.osdd.net/raghava/ccdb) is a manually curated catalog of experimentally validated genes that are thought, or are known to be i...
Subhash M. Agarwal, Dhwani Raghav, Harinder Singh,...
CEC
2005
IEEE
14 years 4 months ago
Multiobjective clustering around medoids
Abstract- The large majority of existing clustering algorithms are centered around the notion of a feature, that is, individual data items are represented by their intrinsic proper...
Julia Handl, Joshua D. Knowles
BMCBI
2006
111views more  BMCBI 2006»
13 years 10 months ago
Development of an unbiased statistical method for the analysis of unigenic evolution
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...
BMCBI
2006
120views more  BMCBI 2006»
13 years 10 months ago
An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
Background: Many statistical algorithms combine microarray expression data and genome sequence data to identify transcription factor binding motifs in the low eukaryotic genomes. ...
Ryung S. Kim, Hongkai Ji, Wing Hung Wong