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» Smoothing Gene Expression Using Biological Networks
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BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
BMCBI
2007
166views more  BMCBI 2007»
13 years 7 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
NAR
2010
111views more  NAR 2010»
13 years 2 months ago
Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional pr
Babelomics is a response to the growing necessity of integrating and analyzing different types of genomic data in an environment that allows an easy functional interpretation of t...
Ignacio Medina, José Carbonell, Luis Pulido...
BIBE
2007
IEEE
162views Bioinformatics» more  BIBE 2007»
14 years 2 months ago
An Investigation into the Feasibility of Detecting Microscopic Disease Using Machine Learning
— The prognosis for many cancers could be improved dramatically if they could be detected while still at the microscopic disease stage. We are investigating the possibility of de...
Mary Qu Yang, Jack Y. Yang
CORR
2010
Springer
139views Education» more  CORR 2010»
13 years 7 months ago
Fast Overlapping Group Lasso
The group Lasso is an extension of the Lasso for feature selection on (predefined) non-overlapping groups of features. The non-overlapping group structure limits its applicability...
Jun Liu, Jieping Ye