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» Statistical analysis of domains in interacting protein pairs
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BMCBI
2007
109views more  BMCBI 2007»
13 years 7 months ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat
KDD
2004
ACM
126views Data Mining» more  KDD 2004»
14 years 8 months ago
High-throughput Protein Interactome Data: Minable or Not?
There is an emerging trend in post-genome biology to study the collection of thousands of protein interaction pairs (protein interactome) derived from high-throughput experiments....
Jake Yue Chen, Andrey Y. Sivachenko, Lang Li
RECOMB
2006
Springer
14 years 8 months ago
Assessing Significance of Connectivity and Conservation in Protein Interaction Networks
Computational and comparative analysis of protein-protein interaction (PPI) networks enable understanding of the modular organization of the cell through identification of functio...
Mehmet Koyutürk, Ananth Grama, Wojciech Szpan...
BMCBI
2005
86views more  BMCBI 2005»
13 years 7 months ago
Confirmation of human protein interaction data by human expression data
Background: With microarray technology the expression of thousands of genes can be measured simultaneously. It is well known that the expression levels of genes of interacting pro...
Andreas Hahn, Jörg Rahnenführer, Priti T...
BMCBI
2004
174views more  BMCBI 2004»
13 years 7 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar