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    BMCBI
    2007
    123views more  BMCBI 2007»
    PedGenie: meta genetic association testing in mixed family and case-control designs
    13 years 11 months ago
    PedGenie: meta genetic association testing in mixed family and case-control designs
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    Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
    Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...
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    BMCBI
    2008
    178views more  BMCBI 2008»
    Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate vi
    13 years 11 months ago
    Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate vi
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    Background: The DNA microarray technology allows the measurement of expression levels of thousands of genes under tens/hundreds of different conditions. In microarray data, genes ...
    Kin-On Cheng, Ngai-Fong Law, Wan-Chi Siu, Alan Wee...
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    BMCBI
    2010
    136views more  BMCBI 2010»
    Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
    13 years 11 months ago
    Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
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    Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
    Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
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    BMCBI
    2010
    94views more  BMCBI 2010»
    Comparison study of microarray meta-analysis methods
    13 years 11 months ago
    Comparison study of microarray meta-analysis methods
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    Background: Meta-analysis methods exist for combining multiple microarray datasets. However, there are a wide range of issues associated with microarray meta-analysis and a limite...
    Anna Campain, Yee Hwa Yang
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    BMCBI
    2010
    135views more  BMCBI 2010»
    Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
    13 years 11 months ago
    Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
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    Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
    Vincent A. Emanuele II, Brian M. Gurbaxani
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