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» The Protein Information Resource (PIR)
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BMCBI
2008
122views more  BMCBI 2008»
13 years 8 months ago
OpenDMAP: An open source, ontology-driven concept analysis engine, with applications to capturing knowledge regarding protein tr
Background: Information extraction (IE) efforts are widely acknowledged to be important in harnessing the rapid advance of biomedical knowledge, particularly in areas where import...
Lawrence Hunter, Zhiyong Lu, James Firby, William ...
CONCURRENCY
2004
93views more  CONCURRENCY 2004»
13 years 8 months ago
Studying protein folding on the Grid: experiences using CHARMM on NPACI resources under Legion
-- One of the benefits of a computational grid is the ability to run high-performance applications over distributed resources simply and securely. We demonstrated this benefit with...
Anand Natrajan, Michael Crowley, Nancy Wilkins-Die...
BMCBI
2007
155views more  BMCBI 2007»
13 years 8 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
NAR
2011
227views Computer Vision» more  NAR 2011»
13 years 3 months ago
VnD: a structure-centric database of disease-related SNPs and drugs
Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and fu...
Jin Ok Yang, Sangho Oh, Gunhwan Ko, Seong-Jin Park...
BMCBI
2006
120views more  BMCBI 2006»
13 years 8 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner