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BMCBI
2004
101views more  BMCBI 2004»
13 years 8 months ago
A database for G proteins and their interaction with GPCRs
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...
Antigoni L. Elefsinioti, Pantelis G. Bagos, Ioanni...
NAR
2006
75views more  NAR 2006»
13 years 8 months ago
DrugBank: a comprehensive resource for in silico drug discovery and exploration
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug (i.e. chemical)data withcomprehensive drug target (i.e.protein) information. The database ...
David S. Wishart, Craig Knox, Anchi Guo, Savita Sh...
NAR
2008
118views more  NAR 2008»
13 years 8 months ago
SuperTarget and Matador: resources for exploring drug-target relationships
The molecular basis of drug action is often not well understood. This is partly because the very abundant and diverse information generated in the past decades on drugs is hidden ...
Stefan Günther, Michael Kuhn 0004, Mathias Du...
BIOINFORMATICS
2011
13 years 5 days ago
When the Web meets the cell: using personalized PageRank for analyzing protein interaction networks
Motivation: Enormous, and constantly increasing quantity of biological information is represented in protein interaction network databases. Most of these data are freely accessibl...
Gábor Iván, Vince Grolmusz
NAR
2011
252views Computer Vision» more  NAR 2011»
12 years 11 months ago
BISC: Binary SubComplexes in proteins database
Binary subcomplexes in proteins database (BISC) is a new protein–protein interaction (PPI) database linking up the two communities most active in their characterization: structu...
Thomas Juettemann, Dietlind L. Gerloff