In this paper, derivation of the optimal chemotherapy schedule is formulated and solved as a dynamic optimization problem. For this purpose two models representing the tumour grow...
Cancer is ranked as one of the top killers in all human diseases and continues to have a devastating effect on the population around the globe. Current research efforts are aiming...
—Many dynamical processes can be represented as directed attributed graphs or Petri nets where relationships between various entities are explicitly expressed. Signaling networks...
Bahram Parvin, Nirmalya Ghosh, Laura Heiser, Merri...
Background: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlyi...
Philippe Lamy, Claus L. Andersen, Lars Dyrskjot, N...
Background: High-throughput screening of pharmaceutical compound activity in tissue culture experiments requires time-consuming repeated analysis of the large amounts of data gene...