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BMCBI
2005
97views more  BMCBI 2005»
13 years 8 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan
BMCBI
2007
134views more  BMCBI 2007»
13 years 8 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
BMCBI
2010
154views more  BMCBI 2010»
13 years 8 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
AUSDM
2007
Springer
173views Data Mining» more  AUSDM 2007»
14 years 2 months ago
The Use of Various Data Mining and Feature Selection Methods in the Analysis of a Population Survey Dataset
This paper reports the results of feature reduction in the analysis of a population based dataset for which there were no specific target variables. All attributes were assessed a...
Ellen Pitt, Richi Nayak
BMCBI
2007
120views more  BMCBI 2007»
13 years 8 months ago
Recognition of interferon-inducible sites, promoters, and enhancers
Background: Computational analysis of gene regulatory regions is important for prediction of functions of many uncharacterized genes. With this in mind, search of the target genes...
Elena A. Ananko, Yury V. Kondrakhin, Tatyana I. Me...