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EVOW
2004
Springer
14 years 26 days ago
Iteratively Inferring Gene Regulatory Networks with Virtual Knockout Experiments
Abstract. In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We introduce enhancements to an Evolutionary Algorithm op...
Christian Spieth, Felix Streichert, Nora Speer, An...
RECOMB
2004
Springer
14 years 7 months ago
Finding approximate tandem repeats in genomic sequences
An efficient algorithm is presented for detecting approximate tandem repeats in genomic sequences. The algorithm is based on a flexible statistical model which allows a wide range...
Ydo Wexler, Zohar Yakhini, Yechezkel Kashi, Dan Ge...
GECCO
2004
Springer
150views Optimization» more  GECCO 2004»
14 years 26 days ago
Systems Biology Modeling in Human Genetics Using Petri Nets and Grammatical Evolution
Understanding the hierarchical relationships among biochemical, metabolic, and physiological systems in the mapping between genotype and phenotype is expected to improve the diagno...
Jason H. Moore, Lance W. Hahn
APBC
2004
163views Bioinformatics» more  APBC 2004»
13 years 9 months ago
A Combined Model and a Varied Gibbs Sampling Algorithm Used for Motif Discovery
The conserved sequences in gene regulatory regions dominate gene regulation. Discovering these sequences and their functions is important in post genome era. A novel model is cons...
Xiaoming Wu, Bo Wang, Changxin Song, Jingzhi Cheng
BMCBI
2004
81views more  BMCBI 2004»
13 years 7 months ago
Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis
Background: Mutations in rpoB, the gene encoding the subunit of DNA-dependent RNA polymerase, are associated with rifampin resistance in Mycobacterium tuberculosis. Several studi...
Michael P. Cummings, Mark R. Segal