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BMCBI
2005
144views more  BMCBI 2005»
13 years 8 months ago
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
Background: Comparison of data produced on different microarray platforms often shows surprising discordance. It is not clear whether this discrepancy is caused by noisy data or b...
Scott L. Carter, Aron C. Eklund, Brigham H. Mecham...
RECOMB
2007
Springer
14 years 8 months ago
A Feature-Based Approach to Modeling Protein-DNA Interactions
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position spe...
Eilon Sharon, Eran Segal
BMCBI
2007
179views more  BMCBI 2007»
13 years 8 months ago
rMotifGen: random motif generator for DNA and protein sequences
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Eric C. Rouchka, C. Timothy Hardin
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Comparative analysis of long DNA sequences by per element information content using different contexts
Background: Features of a DNA sequence can be found by compressing the sequence under a suitable model; good compression implies low information content. Good DNA compression mode...
Trevor I. Dix, David R. Powell, Lloyd Allison, Jul...
BMCBI
2005
126views more  BMCBI 2005»
13 years 8 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois