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ICASSP
2011
IEEE
14 years 7 months ago
Message-passing for base-calling in sequencing-by-synthesis systems
Performance of DNA sequencing-by-synthesis systems is fundamentally limited by the stochastic nature of the underlying biochemical process. We develop a novel graphical representa...
Sang Hyun Lee, Manohar Shamaiah, Haris Vikalo
129
Voted
CORR
2011
Springer
193views Education» more  CORR 2011»
14 years 10 months ago
On the regularity of iterated hairpin completion of a single word
Hairpin completion is an abstract operation modeling a DNA biooperation which receives as input a DNA strand w = xαyα, and outputs w = xαy¯αx, where x denotes the Watson-Cric...
Lila Kari, Steffen Kopecki, Shinnosuke Seki
129
Voted
NAR
2011
186views Computer Vision» more  NAR 2011»
14 years 6 months ago
TcoF-DB: dragon database for human transcription co-factors and transcription factor interacting proteins
The initiation and regulation of transcription in eukaryotes is complex and involves a large number of transcription factors (TFs), which are known to bind to the regulatory regio...
Ulf Schaefer, Sebastian Schmeier, Vladimir B. Baji...
145
Voted
BMCBI
2011
14 years 7 months ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
ICSE
2012
IEEE-ACM
13 years 5 months ago
Engineering and verifying requirements for programmable self-assembling nanomachines
—We propose an extension of van Lamsweerde’s goal-oriented requirements engineering to the domain of programmable DNA nanotechnology. This is a domain in which individual devic...
Robyn R. Lutz, Jack H. Lutz, James I. Lathrop, Tit...