BMCBI
2011
13 years 2 months ago
2011
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
BMCBI
2011
13 years 2 months ago
2011
Background: Cross-platform analysis of gene express data requires multiple, intricate processes at different layers with various platforms. However, existing tools handle only a s...
BMCBI
2011
13 years 2 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
BMCBI
2011
13 years 2 months ago
2011
BMCBI
2011
13 years 2 months ago
2011
BMCBI
2011
13 years 2 months ago
2011
Background: Relative isotope abundance quantification, which can be used for peptide identification and differential peptide quantification, plays an important role in liquid chro...
BMCBI
2011
13 years 2 months ago
2011
Background: Gene set enrichment testing has helped bridge the gap from an individual gene to a systems biology interpretation of microarray data. Although gene sets are defined a ...
BMCBI
2011
13 years 2 months ago
2011
Background: Since its inception, proteomics has essentially operated in a discovery mode with the goal of identifying and quantifying the maximal number of proteins in a sample. I...
BMCBI
2011
13 years 2 months ago
2011
Background: Illumina’s Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw all...
BMCBI
2011
13 years 2 months ago
2011
Background: Bioinformatic analyses typically proceed as chains of data-processing tasks. A pipeline, or ‘workflow’, is a well-defined protocol, with a specific structure defin...