BMCBI
2011
13 years 2 months ago
2011
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
BMCBI
2011
13 years 2 months ago
2011
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
BMCBI
2011
13 years 2 months ago
2011
Background: Visualization of orthogonal (disjoint) or overlapping datasets is a common task in bioinformatics. Few tools exist to automate the generation of extensively-customizab...
BMCBI
2011
13 years 2 months ago
2011
Background: The increasing availability of molecular sequence data means that the accuracy of future phylogenetic studies is likely to by limited by systematic bias and taxon choi...
BMCBI
2011
13 years 2 months ago
2011
BMCBI
2011
13 years 2 months ago
2011
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
BMCBI
2011
13 years 2 months ago
2011
Background: The Distributed Annotation System (DAS) has proven to be a successful way to publish and share biological data. Although there are more than 750 active registered serv...
BMCBI
2011
13 years 2 months ago
2011
Background: The identification of binding targets for proteins using ChIP-Seq has gained popularity as an alternative to ChIP-chip. Sequencing can, in principle, eliminate artifac...
BMCBI
2011
13 years 2 months ago
2011
Background: Building repositories of computational models of biological systems ensures that published models are available for both education and further research, and can provid...
BMCBI
2011
13 years 2 months ago
2011
Background: With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these mol...