This paper presents an algorithm for combining pattern recognition-based exon prediction and database homologysearch in gene model construction. Thegoal is to use homologousgeneso...
Several computeralgorithms for discovering patterns in groups of protein sequences are in use that are basedon fitting the parametersof a statistical model to a group of related s...
Thispaperintroducesa methodfor identifyingempirically conservedaminoacid substitution groups.In contrast with existing approachesthat viewaminoacid substitution as a pairwisepheno...
Weconsider the problemof automaticdiscoveryof patterns and the corresponding subfamilies in a set of biosequences. Thesequences are unaligned and may contain noise of unknownlevel...
Alvis Brazma, Inge Jonassen, Esko Ukkonen, Jaak Vi...
Virtually all large-scale sequencing projects use automatic sequence-assembly programs to aid in the determination of DNA sequences. The computer-generated assemblies require subs...
Carolyn F. Allex, Schuyler F. Baldwin, Jude W. Sha...
Sequencealignmentwithoutthe specification of gap penaltiesor a scoringmatrixis attainedbyusing Bayesianinferenceanda recursivealgorithm.Thisprocedure’srecursivealgorithmsumsover...
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Abstract.) Ying Xu, Richard J. MuraF, and Edward C. Uberbacher Computer Science and Mathematics Division and tLife Sciences Division Computational methods for gene identification ...