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APBC
2004
121views Bioinformatics» more  APBC 2004»
13 years 8 months ago
Using Emerging Pattern Based Projected Clustering and Gene Expression Data for Cancer Detection
Using gene expression data for cancer detection is one of the famous research topics in bioinformatics. Theoretically, gene expression data is capable to detect all types of early...
Larry T. H. Yu, Fu-Lai Chung, Stephen Chi-fai Chan...
APBC
2004
13 years 8 months ago
PathwayFinder: Paving the Way Towards Automatic Pathway Extraction
Automatically mining protein pathway information from the vast amount of published literature has been an increasing need from the pharmaceutical industry and biomedical research ...
Daming Yao, Jingbo Wang, Yanmei Lu, Nathan Noble, ...
APBC
2004
123views Bioinformatics» more  APBC 2004»
13 years 8 months ago
Empirical Knowledge and Genetic Algorithms for Selection of Amide I Frequencies in Protein Secondary Structure Prediction
Here we investigate an extension of a previously suggested "automatic amide I frequency selection procedure" where we introduce an additional criterion utilizing empiric...
Joachim A. Hering, Peter R. Innocent, Parvez I. Ha...
APBC
2004
117views Bioinformatics» more  APBC 2004»
13 years 8 months ago
Detecting Local Symmetry Axis in 3-dimensional Virus Structures
This paper presents an efficient computational method to identify a local symmetry axis in 3-dimensional viral structures obtained using electron cryomicroscopy. Local symmetry is...
Jing He, Desh Ranjan, Wen Jiang, Wah Chiu, Michael...
APBC
2004
163views Bioinformatics» more  APBC 2004»
13 years 8 months ago
A Combined Model and a Varied Gibbs Sampling Algorithm Used for Motif Discovery
The conserved sequences in gene regulatory regions dominate gene regulation. Discovering these sequences and their functions is important in post genome era. A novel model is cons...
Xiaoming Wu, Bo Wang, Changxin Song, Jingzhi Cheng
APBC
2004
116views Bioinformatics» more  APBC 2004»
13 years 8 months ago
Evolving Genetic Regulatory Networks Using an Artificial Genome
Boolean models of genetic regulatory networks (GRNs) have been shown to exhibit many of the characteristic dynamics of real GRNs, with gene expression patterns settling to point a...
Jennifer Hallinan, Janet Wiles
APBC
2004
13 years 8 months ago
A Rapid Method of Whole Genome Visualisation Illustrating Features in Both Coding and Non-coding Regions
The application of Fourier analysis to a genome can be used as an indicator of gene coding regions. We have developed a visualisation of the Fourier spectra that allows convenient...
Ross Hall, Linda Stern
APBC
2004
166views Bioinformatics» more  APBC 2004»
13 years 8 months ago
A Novel Method for Protein Subcellular Localization Based on Boosting and Probabilistic Neural Network.
Subcellular localization is a key functional characteristic of proteins. An automatic, reliable and efficient prediction system for protein subcellular localization is needed for ...
Jian Guo, Yuanlie Lin, Zhirong Sun
APBC
2004
166views Bioinformatics» more  APBC 2004»
13 years 8 months ago
THEMATICS is Effective for Active Site Prediction in Comparative Model Structures
THEMATICS (Theoretical Microscopic Titration Curves) is a simple, reliable computational predictor of the active sites of enzymes from structure. Our method, based on well-establi...
Ihsan A. Shehadi, Alper Uzun, Leonel F. Murga, Val...
APBC
2004
132views Bioinformatics» more  APBC 2004»
13 years 8 months ago
A Novel Feature Selection Method to Improve Classification of Gene Expression Data
This paper introduces a novel method for minimum number of gene (feature) selection for a classification problem based on gene expression data with an objective function to maximi...
Liang Goh, Qun Song, Nikola K. Kasabov