Different mechanisms that could form the molecular basis for bi-directional synaptic plasticity have been identified experimentally and corresponding biophysical models can be cons...
Harel Z. Shouval, Gastone C. Castellani, Brian S. ...
Spike-timing-dependent plasticity (STDP) strengthens synapses that are activated immediately before a postsynaptic spike, and weakens those that are activated after a spike. To pre...
Abstract. How do humans achieve the precise positioning of the feet during walking, for example, to reach the first step of a stairway? We addressed this question at the visuomotor...
A. de Rugy, G. Taga, G. Montagne, M. J. Buekers, M...
Association of a presynaptic spike with a postsynaptic spike can lead to changes in synaptic efficacy that are highly dependent on the relative timing of the preand postsynaptic sp...
The importance of the hippocampus in spatial representation is well established. It is suggested that the rodent hippocampal network should provide an optimal substrate for the stu...
Colin Lever, Neil Burgess, Francesca Cacucci, Tom ...
Abstract. Sensory experience alters the functional organization of cortical networks. Previous studies using behavioral training motivated by aversive or rewarding stimuli have dem...
Michael P. Kilgard, Pritesh K. Pandya, Navzer D. E...
Abstract. Recent experimental observations of spiketiming-dependent synaptic plasticity (STDP) have revitalized the study of synaptic learning rules. The most surprising aspect of ...
Hebb's original postulate left two important issues unaddressed: (i) what is the effective time window between pre- and postsynaptic activity that will result in potentiation?...
Uma R. Karmarkar, Mark T. Najarian, Dean V. Buonom...
Several formulations of correlation-based Hebbian learning are reviewed. On the presynaptic side, activity is described either by a firing rate or by presynaptic spike arrival. The...