Sciweavers

CSB
2004
IEEE
141views Bioinformatics» more  CSB 2004»
13 years 11 months ago
MinPD: Distance-Based Phylogenetic Analysis and Recombination Detection of Serially-Sampled HIV Quasispecies
A new computational method to study within-host viral evolution is explored to better understand the evolution and pathogenesis of viruses. Traditional phylogenetic tree methods a...
Patricia Buendia, Giri Narasimhan
CSB
2004
IEEE
125views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Gene Length and Alternative Transcription in Fruit Fly
Alternative transcription, in which a single gene may give rise to multiple variant mRNA forms, is widely recognized as an important source of protein diversity in complex, eukary...
Boris Budagyan, Ann E. Loraine
CSB
2004
IEEE
115views Bioinformatics» more  CSB 2004»
13 years 11 months ago
PoPS: A Computational Tool for Modeling and Predicting Protease Specificity
Proteases play a fundamental role in the control of intra- and extracellular processes by binding and cleaving specific amino acid sequences. Identifying these targets is extremel...
Sarah E. Boyd, Maria J. García de la Banda,...
CSB
2004
IEEE
113views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Shannon Information in Complete Genomes
Shannon information in the genomes of all completely sequenced prokaryotes and eukaryotes are measured in word lengths of two to ten letters. It is found that in a scale-dependent...
Chang-Heng Chang, Li-Ching Hsieh, Ta-Yuan Chen, Ho...
CSB
2004
IEEE
142views Bioinformatics» more  CSB 2004»
13 years 11 months ago
FastR: Fast Database Search Tool for Non-Coding RNA
The discovery of novel non-coding RNAs has been among the most exciting recent developments in Biology. Yet, many more remain undiscovered. It has been hypothesized that there is ...
Vineet Bafna, Shaojie Zhang
BIBE
2004
IEEE
13 years 11 months ago
Phylogenetic Reconstruction from Arbitrary Gene-Order Data
Phylogenetic reconstruction from gene-order data has attracted attention from both biologists and computer scientists over the last few years. So far, our software suite GRAPPA is...
Jijun Tang, Bernard M. E. Moret, Liying Cui, Claud...
BIBE
2004
IEEE
107views Bioinformatics» more  BIBE 2004»
13 years 11 months ago
Enhanced pClustering and Its Applications to Gene Expression Data
Clustering has been one of the most popular methods to discover useful biological insights from DNA microarray. An interesting paradigm is simultaneous clustering of both genes an...
Sungroh Yoon, Christine Nardini, Luca Benini, Giov...
BIBE
2004
IEEE
115views Bioinformatics» more  BIBE 2004»
13 years 11 months ago
Discovering Novel Interacting Motif Pairs from Large Protein-Protein Interaction Datasets
Current motif discovery methods can only detect individual motifs in groups of protein sequences--they do not discover potentially-interacting motif pairs underlying the interacti...
Soon-Heng Tan, Wing-Kin Sung, See-Kiong Ng
BIBE
2004
IEEE
120views Bioinformatics» more  BIBE 2004»
13 years 11 months ago
Identifying Projected Clusters from Gene Expression Profiles
In microarray gene expression data, clusters may hide in subspaces. Traditional clustering algorithms that make use of similarity measurements in the full input space may fail to ...
Kevin Y. Yip, David W. Cheung, Michael K. Ng, Kei-...