BMCBI
2002
13 years 11 months ago
2002
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
BMCBI
2002
13 years 11 months ago
2002
Background: High-density oligonucleotide arrays have become a valuable tool for highthroughput gene expression profiling. Increasing the array information density and improving th...
BMCBI
2002
13 years 11 months ago
2002
Background: Improvements in DNA sequencing technology and methodology have led to the rapid expansion of databases comprising DNA sequence, gene and genome data. Lower operational...
BMCBI
2002
13 years 11 months ago
2002
Background: Affymetrix microarrays are used by many laboratories to generate gene expression
BMCBI
2002
13 years 11 months ago
2002
Background: A method to evaluate and analyze the massive data generated by series of microarray experiments is of utmost importance to reveal the hidden patterns of gene expressio...
BMCBI
2002
13 years 11 months ago
2002
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
BMCBI
2002
13 years 11 months ago
2002
Background: The availability of biomedical literature in electronic format has made it possible to implement automatic text processing methods to expose implicit relationships amo...
BMCBI
2002
13 years 11 months ago
2002
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
BMCBI
2002
13 years 11 months ago
2002
Background: Recently, Almeida and Vinga offered a new approach for the representation of arbitrary discrete sequences, referred to as Universal Sequence Maps (USM), and discussed ...