Sciweavers

BMCBI
2002
101views more  BMCBI 2002»
13 years 11 months ago
Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
Background: Total sequence decomposition, using the web-based MASIA tool, identifies areas of conservation in aligned protein sequences. By structurally annotating these motifs, t...
Catherine H. Schein, Numan Özgün, Tadahi...
BMCBI
2002
99views more  BMCBI 2002»
13 years 11 months ago
FunSpec: a web-based cluster interpreter for yeast
Background: For effective exposition of biological information, especially with regard to analysis of large-scale data types, researchers need immediate access to multiple categor...
Mark D. Robinson, Jörg Grigull, Naveed Mohamm...
BMCBI
2002
100views more  BMCBI 2002»
13 years 11 months ago
An algorithm and program for finding sequence specific oligo-nucleotide probes for species identification
Background: The identification of species or species groups with specific oligo-nucleotides as molecular signatures is becoming increasingly popular for bacterial samples. However...
Alexander E. Pozhitkov, Diethard Tautz
BMCBI
2002
136views more  BMCBI 2002»
13 years 11 months ago
Making sense of EST sequences by CLOBBing them
Background: Expressed sequence tags (ESTs) are single pass reads from randomly selected cDNA clones. They provide a highly cost-effective method to access and identify expressed g...
John Parkinson, David B. Guiliano, Mark L. Blaxter
BMCBI
2002
188views more  BMCBI 2002»
13 years 11 months ago
The limit fold change model: A practical approach for selecting differentially expressed genes from microarray data
Background: The biomedical community is developing new methods of data analysis to more efficiently process the massive data sets produced by microarray experiments. Systematic an...
David M. Mutch, Alvin Berger, Robert Mansourian, A...
BMCBI
2002
95views more  BMCBI 2002»
13 years 11 months ago
The functional importance of disease-associated mutation
Background: For many years, scientists believed that point mutations in genes are the genetic switches for somatic and inherited diseases such as cystic fibrosis, phenylketonuria ...
Sean D. Mooney, Teri E. Klein
BMCBI
2002
129views more  BMCBI 2002»
13 years 11 months ago
SeqHound: biological sequence and structure database as a platform for bioinformatics research
Background: SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platfor...
Katerina Michalickova, Gary D. Bader, Michel Dumon...
BMCBI
2002
120views more  BMCBI 2002»
13 years 11 months ago
tacg - a grep for DNA
Background: Pattern matching is the core of bioinformatics; it is used in database searching, restriction enzyme mapping, and finding open reading frames. It is done repeatedly ov...
Harry Mangalam
BMCBI
2002
119views more  BMCBI 2002»
13 years 11 months ago
Microarray results: how accurate are they?
Background: DNA microarray technology is a powerful technique that was recently developed in order to analyze thousands of genes in a short time. Presently, microarrays, or chips,...
Ravi Kothapalli, Sean J. Yoder, Shrikant Mane, Tho...