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BMCBI
2002
147views more  BMCBI 2002»
13 years 11 months ago
Expression profiling of human renal carcinomas with functional taxonomic analysis
Background: Molecular characterization has contributed to the understanding of the inception, progression, treatment and prognosis of cancer. Nucleic acid array-based technologies...
Michael A. Gieseg, Theresa Cody, Michael Z. Man, S...
BMCBI
2002
51views more  BMCBI 2002»
13 years 11 months ago
Prediction of MHC class I binding peptides, using SVMHC
Pierre Dönnes, Arne Elofsson
BMCBI
2002
108views more  BMCBI 2002»
13 years 11 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
BMCBI
2002
81views more  BMCBI 2002»
13 years 11 months ago
Species-specific protein sequence and fold optimizations
Background: An organism's ability to adapt to its particular environmental niche is of fundamental importance to its survival and proliferation. In the largest study of its k...
Michel Dumontier, Katerina Michalickova, Christoph...
BMCBI
2002
59views more  BMCBI 2002»
13 years 11 months ago
NBLAST: a cluster variant of BLAST for NxN comparisons
Michel Dumontier, Christopher W. V. Hogue
BMCBI
2002
128views more  BMCBI 2002»
13 years 11 months ago
Correlating overrepresented upstream motifs to gene expression: a computational approach to regulatory element discovery in euka
Background: Gene regulation in eukaryotes is mainly effected through transcription factors binding to rather short recognition motifs generally located upstream of the coding regi...
Michele Caselle, Ferdinando Di Cunto, Paolo Prover...
BMCBI
2002
109views more  BMCBI 2002»
13 years 11 months ago
Kangaroo - A pattern-matching program for biological sequences
Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do no...
Doron Betel, Christopher W. V. Hogue
BMCBI
2002
75views more  BMCBI 2002»
13 years 11 months ago
Quantifying robustness of biochemical network models
Background: Robustness of mathematical models of biochemical networks is important for validation purposes and can be used as a means of selecting between different competing mode...
Lan Ma, Pablo A. Iglesias