BMCBI
2004
13 years 7 months ago
2004
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
BMCBI
2004
13 years 7 months ago
2004
Background: A common clustering method in the analysis of gene expression data has been hierarchical clustering. Usually the analysis involves selection of clusters by cutting the...
BMCBI
2004
13 years 7 months ago
2004
Background: Screening of various gene markers such as single nucleotide polymorphism (SNP) and correlation between these markers and development of multifactorial disease have pre...
BMCBI
2004
13 years 7 months ago
2004
Background: When DNA microarray data are used for gene clustering, genotype/phenotype correlation studies, or tissue classification the signal intensities are usually transformed ...
BMCBI
2004
13 years 7 months ago
2004
BMCBI
2004
13 years 7 months ago
2004
Background: Rates of substitution in protein-coding sequences can provide important insights into evolutionary processes that are of biomedical and theoretical interest. Increased...
BMCBI
2004
13 years 7 months ago
2004
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
BMCBI
2004
13 years 7 months ago
2004
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
BMCBI
2004
13 years 7 months ago
2004
Background: Recent technological advances in high-throughput data collection allow for experimental study of increasingly complex systems on the scale of the whole cellular genome...
