BMCBI
2006
13 years 11 months ago
2006
Background: In this study, we present a robust and reliable computational method for tag-togene assignment in serial analysis of gene expression (SAGE). The method relies on curre...
BMCBI
2006
13 years 11 months ago
2006
Background: The Lepidoptera Spodoptera frugiperda is a pest which causes widespread economic damage on a variety of crop plants. It is also well known through its famous Sf9 cell ...
BMCBI
2006
2006
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
13 years 11 months ago
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
BMCBI
2006
13 years 11 months ago
2006
Background: Autoimmune diseases are disorders caused by an immune response directed against the body's own organs, tissues and cells. In practice more than 80 clinically dist...
BMCBI
2006
13 years 11 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
BMCBI
2006
13 years 11 months ago
2006
Background: A complete understanding of the regulatory mechanisms of gene expression is the next important issue of genomics. Many bioinformaticians have developed methods and alg...
BMCBI
2006
13 years 11 months ago
2006
Background: Single nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. ...
BMCBI
2006
13 years 11 months ago
2006
Background: Phylogenetic methods which do not rely on multiple sequence alignments are important tools in inferring trees directly from completely sequenced genomes. Here, we exte...
BMCBI
2006
13 years 11 months ago
2006
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
BMCBI
2006
13 years 11 months ago
2006
