Sciweavers

BMCBI
2006
128views more  BMCBI 2006»
13 years 11 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
BMCBI
2006
154views more  BMCBI 2006»
13 years 11 months ago
Agile methods in biomedical software development: a multi-site experience report
Background: Agile is an iterative approach to software development that relies on strong collaboration and automation to keep pace with dynamic environments. We have successfully ...
David W. Kane, Moses M. Hohman, Ethan G. Cerami, M...
BMCBI
2006
144views more  BMCBI 2006»
13 years 11 months ago
Association algorithm to mine the rules that govern enzyme definition and to classify protein sequences
Background: The number of sequences compiled in many genome projects is growing exponentially, but most of them have not been characterized experimentally. An automatic annotation...
Shih-Hau Chiu, Chien-Chi Chen, Gwo-Fang Yuan, Thy-...
BMCBI
2006
124views more  BMCBI 2006»
13 years 11 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
BMCBI
2006
110views more  BMCBI 2006»
13 years 11 months ago
CpGcluster: a distance-based algorithm for CpG-island detection
Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...
BMCBI
2006
143views more  BMCBI 2006»
13 years 11 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
BMCBI
2006
161views more  BMCBI 2006»
13 years 11 months ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang
BMCBI
2006
112views more  BMCBI 2006»
13 years 11 months ago
Argument-predicate distance as a filter for enhancing precision in extracting predications on the genetic etiology of disease
Background: Genomic functional information is valuable for biomedical research. However, such information frequently needs to be extracted from the scientific literature and struc...
Marco Masseroli, Halil Kilicoglu, François-...
BMCBI
2006
94views more  BMCBI 2006»
13 years 11 months ago
Dynamic variable selection in SNP genotype autocalling from APEX microarray data
Background: Single nucleotide polymorphisms (SNPs) are DNA sequence variations, occurring when a single nucleotide
Mohua Podder, William J. Welch, Ruben H. Zamar, Sc...