Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
Background: Agile is an iterative approach to software development that relies on strong collaboration and automation to keep pace with dynamic environments. We have successfully ...
David W. Kane, Moses M. Hohman, Ethan G. Cerami, M...
Background: The number of sequences compiled in many genome projects is growing exponentially, but most of them have not been characterized experimentally. An automatic annotation...
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Background: Genomic functional information is valuable for biomedical research. However, such information frequently needs to be extracted from the scientific literature and struc...